Publications - Eir Biotherapies

Guiho R, Biteau K, Grisendi G, Taurelle J, Chatelais M, Gantier M, Heymann D, Dominici M, Redini F. TRAIL delivered by mesenchymal stromal/stem cells counteracts tumor development in orthotopic Ewing sarcoma models. Int J Cancer. 2016 Dec 15;139(12):2802-2811. doi: 10.1002/ijc.30402.

Relation T, Dominici M, Horwitz EM. Concise Review: An (Im)Penetrable Shield: How the Tumor Microenvironment Protects Cancer Stem Cells. Stem Cells. 2017 May;35(5):1123-1130. doi: 10.1002/stem.2596.

Rossignoli F, Grisendi G, Spano C, Golinelli G, Recchia A, Rovesti G, Orsi G, Veronesi E, Horwitz EM, Dominici M. Inducible Caspase9-mediated suicide gene for MSC-based cancer gene therapy. Cancer Gene Ther. 2019 Feb;26(1-2):11-16. doi: 10.1038/s41417-018-0034-1. Epub 2018 Jun 29.

Golinelli G, Grisendi G, Prapa M, Bestagno M, Spano C, Rossignoli F, Bambi F, Sardi I, Cellini M, Horwitz EM, Feletti A, Pavesi G, Dominici M. Targeting GD2-positive glioblastoma by chimeric antigen receptor empowered mesenchymal progenitors. Cancer Gene Ther. 2018 Nov 22. doi: 10.1038/s41417-018-0062-x.

Spano C, Grisendi G, Golinelli G, Rossignoli F, Prapa M, Bestagno M, Candini O, Petrachi T, Recchia A, Miselli F, Rovesti G, Orsi G, Maiorana A, Manni P, Veronesi E, Piccinno MS, Murgia A, Pinelli M, Horwitz EM, Cascinu S, Conte P, Dominici M. Soluble TRAIL Armed Human MSC As Gene Therapy For Pancreatic Cancer. Sci Rep. 2019 Feb 11;9(1):1788. doi: 10.1038/s41598-018-37433-6.

Rossignoli F, Spano C, Grisendi G, Foppiani EM, Golinelli G, Mastrolia I, Bestagno M, Candini O, Petrachi T, Recchia A, Miselli F, Rovesti G, Orsi G, Veronesi E, Medici G, Petocchi B, Pinelli M, Horwitz EM, Conte P, Dominici M. MSC-Delivered Soluble TRAIL and Paclitaxel as Novel Combinatory Treatment for Pancreatic Adenocarcinoma. Theranostics 2019; 9(2):436-448. doi:10.7150/thno.27576.

Candini O, Grisendi G, Foppiani EM, Brogli M, Aramini B, Masciale V, Spano C, Petrachi T, Veronesi E, Conte P, Mari G, Dominici M. A Novel 3D In Vitro platform for pre-Clinical Investigations in Drug Testing, Gene Therapy, and Immuno-oncology. Scientific Reports 9:7154 (2019) doi: 10.1038/s41598-019-43613-9.

Golinelli G, Mastrolia I, Aramini B, Masciale V, Pinelli M, Pacchioni L, Casari G, Dall’Ora M, Soares MBP, Damasceno PKF, Silva DN, Dominici M and Grisendi G. Arming Mesenchymal Stromal/Stem Cells Against Cancer: Has the Time Come? Front. Pharmacol., 29 September 2020 | https://doi.org/10.3389/fphar.2020.529921.

Massimiliano Dall’Ora, Giulia Rovesti, Luca Reggiani Bonetti, Giulia Casari, Federico Banchelli, Luca Fabbiani, Elena Veronesi, Tiziana Petrachi, Paolo Magistri, Fabrizio Di Benedetto, Andrea Spallanzani, Chiara Chiavelli, Maria Carlotta Spano, Antonino Maiorana, Massimo Dominici, Giulia Grisendi. TRAIL receptors are expressed in both malignant and stromal cells in pancreatic ductal adenocarcinoma. Am J Cancer Res 2021;11(9):4500-4514 ISSN:2156-6976/ajcr0135860.

Golinelli G, Grisendi G, Dall'Ora M, Casari G, Spano C, Talami R, Banchelli F, Prapa M, Chiavelli C, Rossignoli F, Candini O, D'Amico R, Nasi M, Cossarizza A, Casarini L, Dominici M. Anti-GD2 CAR MSCs against metastatic Ewing's sarcoma. Transl Oncol. 2022 Jan;15(1):101240. doi: 10.1016/j.tranon.2021.101240.